Endocrine Abstracts

Introduction: Graves’ thyrotoxicosis has been known to affect other organ systems in the body including the liver. However, severe hepatitis in this clinical context is quite rare.Case report: We report a 55-year-old man who presented with marked weight loss and jaundice. In addition, he had a diffuse goitre with fine tremors in the hands. Laboratory work-up revealed thyrotoxicosis with FT4 of 87.9 pmol/l and TSH of <0.01 mIU/l. He ha...

Context: Recent studies showed association between hyperaldosteronism and low bone density among patients with primary aldosteronism (PA) due to secondary hyperparathyroidism.Objective: To assess bone turnover markers and bone mineral density (BMD) of PA patients compared to essential hypertension.Design: This was an open label, prospective, case-controlled study, conducted over 12 months.Setting: Eighteen co...

Introduction: Acute myocardial infarction (AMI) is a stressful condition in which it stimulates the hypothalamus-pituitary-adrenal axis leading to mark increase in the production of cortisol. Adrenal insufficiency (AI) has been shown to be associated with morbidity and mortality in acute coronary syndrome patients. To date, none study has been performed to determine prevalence of AI among patient with AMI.Objectives: The aim of this study is to determine...

Introduction: Acute ischaemic stroke is a stressful condition in which there is marked increase in the production of cortisol. In the past adrenal insufficiency in critically ill patients had been shown to be associated with significant morbidity and mortality. To date there is no study performed to determine its prevalence among patients with acute ischaemic stroke.Objectives: The aim of this study is to determine the prevalence of relative adrenal insu...

Introduction: Refined carbohydrates, which constitute the staple diet in most cultures may exaggerate postprandial responses in term of insulin, free fatty acid and vascular function. These changes may contribute the onset of metabolic syndrome and diabetes among those at high risk of developing these diseases.Objective: To determine the postprandial insulin, free fatty acids levels and endothelial function responses in healthy subjects to two different ...